FORMIGA, T. H. C.; http://lattes.cnpq.br/2658546862165877; FORMIGA, Thiago Henrique Carneiro.
Résumé:
The objective of this study was to evaluate the use of chitosan and P-triphosphate calcium
in bone healing by means of clinical evaluation and computed tomography. Therefore, we
used 12 adult rabbits, weighing 3 kg on average. In each animal were made four tibial
osteotomies, one proximal tibia and distal metaphysis of each other tibia. The metaphysis
of the left tibia osteotomy was performed without introducing any biomateiral (control
group) was placed in the osteotomy distal implant chitosan. In proximal metaphyseal
osteotomy of the right tibia was introduced p-triphosphate and calcium in the distal
composite chitosan / P-calcium triphosphate. The animals were evaluated clinically for a
period of 10 days. Meanwhile there was no wound dehiscence and ambulate normally.
After this period the animals were euthanized and the tibias removed for tomographic
analysis. In the tomographic evaluation there was a statistically significant difference (p>
0.05) between groups for time between times or by group, however, the tomographic
images of the implants showed greater radiopacity, which implies a greater amount of
tissue newly formed in relation to the control group.
