FERREIRA, C. R.; http://lattes.cnpq.br/8049470611062660; FERREIRA, Christiany Rodrigues.
Résumé:
Odontogenic keratocyst (CO) is a cystic lesion originated in dental lamina
remais, characterized by its infiltrative pattern, with high recurrence rates. This lesion may be
associated with the Gorlin-Goltz syndrome, which, among other findings, may present multiple
COs in the jaws. The aim of this study was to compare the histopathological aspects of the
epithelial lining cyst of the Non-Syndromic Odontogenic Keratocyst (CONS) and the
syndromic Odontogenic Keratocysts (COS). Methodology: Epithelial thickness analysis was
performed in two ways: by counting cell layers and using software Image J to do the
measurements. The presence of exocytosis was evaluated and classified according to the
presence of inflammatory cells in the epithelial thirds. The mitoses and buddings count was
performed throughout the whole epithelium extension. Results: Fifty-four CO cases were
included in the sample, of which 30 were CONS and 24 were COS cases. No statistically
significant differences in epithelial thickness were identified between groups. The presence of
inflammatory cells in the epithelium (exocytosis) was evidenced in a large part of the sample,
without significant differences between CONSs and COSs. The count of mitoses and buddings
did not find significant statistical differences between the groups. Conclusion: The possible
differences attributed to the COSs found in the literature could not be evidenced by the
histopathological criteria investigated in the epithelium of the cystic coating of the lesions of
this study.