Possíveis problemas relacionados a medicamentos antimicrobianos em um Hospital Público Paraibano.

Abstract

Health Care­Related Infections, when they arise, require adequate treatment, which includes the use of antimicrobials by the patient. However, in this process, prescription errors, adverse reactions, drug interactions may occur, among other situations, which compromise the efficacy and safety of the therapy. Therefore, the objective was to detect possible problems related to antimicrobial drugs (PRM's) used by inpatients in a hospital in Paraíba. Therefore, a prospective, longitudinal and observational study was carried out, from November 2020 to August 2021, through the analysis of medical records and pharmaceutical anamnesis with patients. As for the classification of these problems, the International System Pharmaceutical Care Network Europe (PCNE) version 9.0 was used, considering a systematic assessment of the indication, effectiveness, safety and patient adherence to pharmacological treatment. As a result, 45 inmates were part of the sample, with a predominance of males (51.1%), mean age of 61.2 years, Ceftriaxone as the most used antibiotic for systemic use and with the main MRP being the poor readability of the prescriptions (40 %). Therefore, the results of this work suggest that it is necessary to institute urgent measures to raise the awareness of prescribers, in search of a clear, readable and cohesive prescription, or the adoption of a computerized system, which would consequently contribute to preventing the emergence of MRP, providing safety and well­being of inpatients.