O papel da nutrição na recuperação de pacientes queimados com ênfase na ação biológica da glutamina: uma revisão.

Abstract

The incidence of burns is a public health problem and brings several associated problems, such as metabolic disorders, which lead to dysfunctions such as intense catabolism and hyperglycemia. From this, it is known that nutrition is a way to mitigate these problems. Therefore, this work aims to evaluate the function of nutrition, especially glutamine as an adjunct resource in the recovery of burn patients. This is a bibliographic review of the literature, built from scientific articles obtained from the ScienceDirect, Pubmed and Google academic databases in the English language, using the descriptors “nutrition”, “burn patient”, “glutamine”, using at least Boolean operator “AND” for combinations. Articles corresponding to the last 11 years and within the theme of interest were included and those that did not correspond to these criteria were excluded. After applying the selection criteria, 10 articles were added, which dealt with the application of glutamine as a therapeutic agent in the intervention on burned patients. Glutamine has been shown to improve metabolic changes such as insulin resistance, decreased metabolic markers including cardiac markers. At the intestinal level, it has also been shown to act on intestinal permeability, in order to stimulate the synthesis of mucosal protective agents. In view of this positive effect, this directly impacts the reduction of bacterial translocation and, consequently, reduces the risk of sepsis and infectious processes. Therefore, the positive influence of glutamine in aiding the recovery of burn patients is clear, leading to a better prognosis.