PASCOAL, A. G.; PASCOAL, ALYSSON GUIMARÃES.; MACEDO, L. F.; GURJÃO, M. M.; VITURINO, M. G. M.; VITURINO, MARINA GONÇALVES MONTEIRO.; GONÇALVES MONTEIRO VITURINO.; http://lattes.cnpq.br/2208665450776376; http://lattes.cnpq.br/6202564231545542; http://lattes.cnpq.br/5330032745485012; http://lattes.cnpq.br/5031653464643655; PASCOAL, Alysson Guimarães.; MACEDO, Larissa Ferreira de.; GURJÃO, Mariana Monteiro.; VITURINO, Marina Gonçalves Monteiro.
Résumé:
The pituitary hormone deficiency is characterized by a partial or
complete loss of one or more pituitary hormones of the adenohypophysis and/or
neurohypophysis. When is diagnosed dysfunction of two or more pituitary
hormones, has the so-called multiple pituitary hormone deficiency (MPHD). Its
etiology includes hereditary and acquires causes. Clinial manifestations of
DMHH depend on the extent of hormone deficiency and can be nonspecific or
specific, related of the function of the impaired hormone in question. This study
aims to evaluate, during the period from September 2011 to August 2012, the
central epidemiological chacteristics and clinical presentation of patients with
Multiple Disabilities Ptuitary assisted by the service of Endocrinology and
Metalbolism, Hospital Universitário Alcides Carneiro. Material and Methods:
assessment and evaluation form filling of patients diagnosed with DMHH and
followed the abovementioned service. Results: GH deficiency was more
prevalent among all pituitary hormones, being observed in 100% of patients.
The initial complaint was also more commonly reported related to this hormone,
since short stature is one of the early symptoms that bothers the patient. As for
laboratory findings, hormonal deficiencies have been proven in the following
proportions: GH in all patients, LH and FSH in 12 (70.58%), TSH and ACTH in 8
(47.05%). The correspondences between deficiency and laboratory-related
clinical manifestations were as follows: 94.11% for GH; for LH and FSH
91.66%; 50% for TSH, ACTH 25%. Conclusion: The pattern followed the most
frequent deficiencies of literature, being initially symptoms of GH deficit followed
by symptoms of gonadotropin deficit.