MOURA, D. R.; PATRÍCIO, L. F.; GADELHA, R. L.; DE ALEXANDRIA LEITE, RAISSA MIRANDA.; http://lattes.cnpq.br/4651425841955269; http://lattes.cnpq.br/4600799671493977; http://lattes.cnpq.br/7594809745860879; MOURA, Dannila Ramalho.; PATRÍCIO, Lorena Figueiredo.; GADELHA, Raissa de Lima.; LEITE, Raissa Miranda de Alexandria
Résumé:
Metabolic syndrome is a highly prevalent disorder in the general population, and the
largest association of comorbidities such as obesity, dyslipidemia and diabetes in
patients with psychiatric disorders has been demonstrated by research. This study
aims to evaluate the relationship of metabolic syndrome in schizophrenic patients,
highlighting the risk factors associated with these patients responsible for developing
the syndrome and raise the need for a more rigorous clinical monitoring, considering
other aspects of the health of these patients and not only control of mental illness. We
conducted a literature review of articles containing metabolic syndrome in patients with
schizophrenia in the electronic databases MEDLINE and LILACS, between January
2005 and September 2013. A total of 255 articles, 37 were selected according to the
inclusion criteria and content relevance. Studies show that schizophrenia alone is
considered a risk factor for the development of diabetes. A sedentary lifestyle, poor
diet, smoking and illicit drug abuse contribute to the increased risk of metabolic
syndrome. Allied to these factors, it was demonstrated that treatment with second-
generation antipsychotics are associated with greater weight gain, dyslipidemia and
insulin resistance. Nevertheless, the treatment of individuals with schizophrenia have
been limited to the control of psychotic symptoms. It is therefore essential for stricter
monitoring of these patients for screening and monitoring of risk factors associated
with cardiometabolic alterations.