Hipovitaminose D e alterações cognitivas em idosos: uma revisão sistemática.

Abstract

INTRODUCTION: Vitamin D has its well-established role in bone and calcium metabolism. In our times, several studies have demonstrated its extraskeletal paper, trying to correlate with the development of diseases that present rising prevalence, such as cognitive disorders. Although present in all age groups, vitamin D deficiency is quite common in the elderly. OBJECTIVE: To evaluate the association between cognitive function with the low concentration of vitamin D levels in the elderly. METHODS: We conducted a literature review of articles on correlation of vitamin D deficiency and cognitive impairment in the elderly in electronic databases LILACS, MEDLINE, SciELO, PubMed, Web of Science; published from January 2005 to June 2015, including publications in English, Spanish and Portuguese. Two authors independently extracted data form and quality of the studies using predefined criteria, and the articles that contained animal studies and to include people under the age of 60 years. RESULTS: A total of 35 articles were selected according to predefined criteria. Most of it was classified as excellent or good quality, from the United States and Europe, and cross-sectional studies with patients 60 years or older, disabled Vitamin D and dementia in neurology journals. In total, summing up the work, the population evaluated included the 38.822 individuals. CONCLUSION: The selected studies met in a satisfactory rating in relation to their production of quality (Class A and B), acquiring greater fidelity to the search function of the study.The valued age is above 60 years and insufficient levels of 25 OH vitamin D are shown in these longer present. This work showed up a larger relationship, through the reviewed articles, the association between serum 25 OH vitamin D below 20 ng / mL in the presence of cognitive impairment.