Farmacoterapia em pacientes portadores de glaucoma: uma revisão sistemática.

Abstract

Glaucoma is a disease of unknown etiology characterized by degeneration of axons of the papilla of the optic nerve that can lead to an irreversible blindness. Most often, it is associated to an increased intraocular pressure, being this the only risk factor that is treatable. The treatment consists on maintaining pressure levels that prevent the show up or progression of the optic neuropathy. The ocular hypotensive drugs used are classified due to the action mechanisms, so that some classes of them are more efficient and safe on clinical practice. On the other hand, those drugs display considerable local and/or systemic adverse effects that impacts on patient adherence to the treatment. In this study, we show a systematic review about the drugs used in the clinical therapy, with an emphasis on their local and/or systemic adverse effects.