Desenvolvimento de compósitos de superfície PEUAPM/quitosana: potenciais aplicações biomédicas.

Abstract

The biomateriais have been extensively studied in order to obtain materials having better responses for specific applications, given that the polymeric biomateriais are noted for their similar properties to the fabrics. Among these biomateriais two stand out in a wide biomedical application polyethylene of ultra high molecular weight polyethylene - UHMWPE has high mechanical property that has most limiting factors for certain applications such as chitosan and its chemical inertia that has great biological properties but also limiting factors such as the properties mechanical. In the ongoing search for materials that act more promising a certain application, technological advancement occurs during the emergence of biocomposites combining two or more materials to tailor the properties. To this end it is necessary to frequently modify the surface of a material to promote the interaction thereof. Given these observations emer the idea of developing a composite of UHMWPE / Chitosan to unite the properties of both obtaining a new biomaterial, such for modifying the surface of UHMWPE was performed using two treatments, the chemical hydrogen peroxide for 24 and 48 hours with physical and sanding, and two preparation methods defined by: solvent evaporation by immersing G1 and G2. Thereby obtaining five surfaces of the plates UHMWPE: crude chemically treated for 24h and 48h and physicochemical treatment for 24h and 48h represented by A, B, C, D and E respectively. These surfaces were characterized by FTIR, MO, wettability by contact angle and biological characterization, noting that the treatment altered the surface and does not interfere with its biocompatibility, yet it appears that the UHMWPE modified chemically by hydrogen peroxide in 48h and sanding with sandpaper No. 1200 presented major change. For the development of biocomposite boards from UHMWPE with their corresponding variations have the following samples: AG1, BG1, CG1, DG1, EG1 and AG2, BG2, CG2, DG2, EG2. These composites were characterized by XRD, FTIR and MO, noting that biocomposites both G1 and G2 showed the interaction between the components and the preparation method influences the formation of biocomposite, and the group G2 which proved more consistency in forming the composite. Thus concluding that the chemical treatment and physical chemist is a promising method of surface modification of UHMWPE and this does not change the biological characteristics and the method of preparation influences in forming composite UHMWPE / Chitosan. Keywords: