SILVA, Carlos César da.
Résumé:
From early civilizations the therapeutic potential of the species of the plant kingdom
are known and exploited, either in the form of teas, ointments, or even as modern
medicine today. The species Erythroxylum are known and used in folk medicine for the
treatment of various infections. Staphylococcus aureus and Pseudomonas aeruginosa
are pathogenic microorganisms present in our country and responsible for much of the
community and hospital infections. Its ability to acquire resistance to antibiotics has led
health professionals to an unceasing search for new drugs that can work around this
problem. This research was intended to evaluate the in vitro antibacterial activity of
Erythroxylum subrotundum extract on the species Staphylococcus aureus and
Pseudomonas aeruginosa. Using the technique of microdilution the hydroethanol
extract of the leaves of plant species tested at concentrations of 2000 μg/mL to 15,62
μg/mL. There was no antimicrobial activity against Staphylococcus aureus. The tested
Pseudomonas aeruginosa strains showed sensitivity to the action of extract with an
observed minimum inhibitory concentration of 250 μg/ml.
It is necessary that new studies be conducted to evaluate the action of other fractions
of the extract and that they can be tested against clinical strains of these
microorganisms.
