Estudo in vitrro da ação antibacteriana de Erythroxylum subrotundum sobre Staphylococcus aureus Pseudomonas aeruginosa.

Abstract

From early civilizations the therapeutic potential of the species of the plant kingdom are known and exploited, either in the form of teas, ointments, or even as modern medicine today. The species Erythroxylum are known and used in folk medicine for the treatment of various infections. Staphylococcus aureus and Pseudomonas aeruginosa are pathogenic microorganisms present in our country and responsible for much of the community and hospital infections. Its ability to acquire resistance to antibiotics has led health professionals to an unceasing search for new drugs that can work around this problem. This research was intended to evaluate the in vitro antibacterial activity of Erythroxylum subrotundum extract on the species Staphylococcus aureus and Pseudomonas aeruginosa. Using the technique of microdilution the hydroethanol extract of the leaves of plant species tested at concentrations of 2000 μg/mL to 15,62 μg/mL. There was no antimicrobial activity against Staphylococcus aureus. The tested Pseudomonas aeruginosa strains showed sensitivity to the action of extract with an observed minimum inhibitory concentration of 250 μg/ml. It is necessary that new studies be conducted to evaluate the action of other fractions of the extract and that they can be tested against clinical strains of these microorganisms.