CORREIA, C. K. M.; QUIRINO, E. L. V.; http://lattes.cnpq.br/7929662787808054; http://lattes.cnpq.br/0443667830209280; CORREIA, Cindy Kelly Mendes.; QUIRINO, Euthalia de Lemos Vilela.
Resumen:
Antimicrobial agents have shown their clinical importance by saving countless
people infected by bacteria. In the last decades, there was an emergence of
antimicrobial resistance and its following dissemination across the globe; in
consequence of that, we face important therapy limitation, especially at Intensive
Care Units (ICU). The World Health Organisation (WHO) recognised Antimicrobial
Resistance (AMR) as a global public health crisis. This study aims at providing a
description of antimicrobial resistance characteristics in bacteria isolated from
cultures of inpatients at many facilities in the AlcidesCarneiro University Hospital
(HUAC). An analytical, retrospective, transversal cohort study was created, including
patients' samples sent to cultivation from January 2015 to December 2017, according
to HUAC's laboratory, and the research was crafted from August 2017 to July 2018.
The Mann-Whitney test demonstrated that some wards are similar in regards to the
number of organisms found; however, the adult ICU stands out from other wards.
Enterobacter cloacae was the clinically relevant organism that showed the greatest
resistance, and the drug that caused the greatest resistance was Benzilpeniciline;
Pseudomonas spp. and Klebsiella spp. had high resistance to carbapenems. Other
studies also highlight this reality. Therefore, a progressive increasing on the number
of multiresistant bacteria at the hospital environment is evident, as well as the
utilisation of a big therapeutic arsenal which has contributed to the selection of those
microorganisms, making it necessary that a conscientious and adequate
manipulation of those drugs takes place.
