Perfil de resistência bacteriana em um Hospital Universitário de Campina Grande - PB.

Abstract

Antimicrobial agents have shown their clinical importance by saving countless people infected by bacteria. In the last decades, there was an emergence of antimicrobial resistance and its following dissemination across the globe; in consequence of that, we face important therapy limitation, especially at Intensive Care Units (ICU). The World Health Organisation (WHO) recognised Antimicrobial Resistance (AMR) as a global public health crisis. This study aims at providing a description of antimicrobial resistance characteristics in bacteria isolated from cultures of inpatients at many facilities in the AlcidesCarneiro University Hospital (HUAC). An analytical, retrospective, transversal cohort study was created, including patients' samples sent to cultivation from January 2015 to December 2017, according to HUAC's laboratory, and the research was crafted from August 2017 to July 2018. The Mann-Whitney test demonstrated that some wards are similar in regards to the number of organisms found; however, the adult ICU stands out from other wards. Enterobacter cloacae was the clinically relevant organism that showed the greatest resistance, and the drug that caused the greatest resistance was Benzilpeniciline; Pseudomonas spp. and Klebsiella spp. had high resistance to carbapenems. Other studies also highlight this reality. Therefore, a progressive increasing on the number of multiresistant bacteria at the hospital environment is evident, as well as the utilisation of a big therapeutic arsenal which has contributed to the selection of those microorganisms, making it necessary that a conscientious and adequate manipulation of those drugs takes place.