ARENHARDT, C. R.; FRANÇA, I. M.; FRANÇA, IGOR MACEDO LIMA DE.; http://lattes.cnpq.br/5670616317329260; http://lattes.cnpq.br/4638568655474409; ARENHARDT, Cristian Reinaldo.; FRANÇA, Igor Macedo Lima de.
Resumo:
Hypothyroidism refers to any condition in which the thyroid gland does not produce or
secrete sufficient amounts of thyroxine. This clinical condition, established and in the
subclinical form, is related to several diseases and may give these worse prognosis.
Among the conditions that may be associated with hypothyroidism, one that causes
significant impairment in patients' quality of life is obstructive sleep apnea syndrome
(OSAS), which is related to increased daytime sleepiness, increased risk of
occupational accidents and as well as increased cardiovascular risk and
development of metabolic syndrome (MS) and diabetes mellitus (DM). The aim of this
study is to verify the relationship between hypothyroidism and the increased risk of
developing OSAS, and to determine the presence of risk factors for OSAS in
hypothyroid patients treated at the endocrinology outpatient clinics of the University
Hospital Alcides Carneiro (HUAC), from June 2019 to October 2019. This is an
analytical observational cross-sectional study, in which 43 patients who attended
consultations at the HUAC were asked to answer a questionnaire resulting from the
combination of questions in the Berlin questionnaire and the STOP-Bang
questionnaire, with subsequent determination of the risk of OSAS with the respective
scales of each questionnaire. The subjects participated in the research by signing the
Informed Consent Form (ICF). It was found that patients with hypothyroidism have an
increased risk for OSAS compared to the general population, with a prevalence of
7% (n = 3) of high risk cases, 37.2% (n = 16) of intermediate risk and 55.8% (n = 24)
of low risk by the Stop-Bang questionnaire score. The Berlin questionnaire score
found 39.5% (n = 17) of high-risk cases and 60.5% (n = 26) of low-risk cases. Thus,
51.1% (n = 22) of respondents had some degree of increased risk for OSAS based
on both questionnaires. Among the risk factors, those most related to the onset of
OSAS were age, neck circumference, increased body mass index (BMI) and waist
circumference (WC), daytime sleepiness, and snoring (numbers). It is concluded that
there is a need for more studies, with more representative sample space and using
polysomnography to increase the accuracy of the results, to establish more
accurately the association of OSAS with other health conditions besides
hypothyroidism, and thus assist in the treatment of this syndrome.