MOREIRA, A. D. A.; http://lattes.cnpq.br/9738948323312822; http://lattes.cnpq.br/2175547452275022; MOREIRA, Arthur Diego de Aquino.; SILVA, Felipe Matheus Neves.
Resumen:
Endometrial polyps are focal endometrial growths that form circumscribed masses. In general
population it has a prevalence between 20 to 30%. As for his malignant, present in up to
12.9% in postmenopausal, we find from hyperplastic lesions to endometrial carcinoma. Risk
factors reported for malignancy are age, nulliparity, early menarche, late menopause, large
polyps, use of Tamoxifen and hormone replacement therapy (HRT), Metabolic Syndrome
and the presence of dysfunctional uterine bleeding (DUB). We emphasize the importance of
studying this subject, because despite the higher prevalence in postmenopausal women being
associated with increased malignant rate, the management forward polyps in this age is still
controversial. The research objectives are to evaluate the malignancy rate of endometrial
polyps in women after menopause, and describe, according to the histopathology, the
patient's age, age of menopause, post-menopause time, race, parity, presence of diabetes and /
or hypertension, symptoms (as DUB), and use of Tamoxifen or HRT. This is an
epidemiological, descriptive and cross-sectional study, in which we studied the
postmenopausal patients undergoing hysteroscopy in 2015, with a diagnosis of endometrial
polyp at an University Hospital in Campina Grande-PB. The final sample consisted of 49
patients, 4 of them with adenocarcinoma. In the results, dividing into groups with benign and
malignant histopathology, we find, respectively, the mean age of 60.91 x 58.75 years,
menopause age of 58.68 x 48.5 years, time since menopause of 10 26 x 10.25 years, parity of
3.48 x 1 children, diabetes prevalence of 22 x 0% and hypertension of 57.77 x 25%, uterine
bleeding in 11.11% x 25% and Caucasians as 55 , 5 x 75%. HRT and Tamoxifen were
reported in one patient each, both with benign polyps. We note that the variables of patient
age, age of manopausa , time since menopause , diabetes and hipertesão did not agree with
reports in the literature that highlight them as risk factors. However, the lower parity, white
race and presence of uterine bleeding were actually higher in the group with cancer, as
expected according to the literature in general. More recent analytical studies have questioned
these traditional risk factors , and noted that the presence of DUB is the most reliable and
significant variable. New researches are necessary with a bigger number of patients, in order
to validate the perceptions and approaches on risk factors to this patology, contributing to
reduce gaps between the theory and daily approach