Análise da relação entre o uso de estatinas e declínio cognitivo.

Abstract

Elderly persons, comprising about 11% of Brazilian population, present with high prevalence of chronic degenerative disorders, such as cardiovascular diseases and dementia. Among the risk factor for developing cardiovascular diseases, we highlight hypercholesterolemia, whose pharmacological treatment includes statins, drugs with lipidlowering action. Recent epidemiological data have suggested an association between high cholesterol levels with Alzheimer Disease (AD), the most common cause of dementia, accounting for about 60% to 80% of cases, and other types of dementia, thus a reduction in such levels with statins may have a protective effect on cognitive function. Aims: To assess the relationship between statins usage and cognitive decline (CD).