CAMPOS FILHO, P. V.; SOUZA, T. S.; http://lattes.cnpq.br/1770560731386839; CAMPOS FILHO, Petrônio Vilar.; SOUZA, Tiago Suassuna.
Abstract:
Initiation of antiretroviral therapy (ART) marked a shift in the path of AIDS,
increasing life expectancy and turning HIV infection into a chronic disease. From this
moment some patients entered this long-term relationship with the virus, a correlation
of HIV with atherosclerosis was observed, attributed mainly to the pro-inflammatory
state provoked by the infection. In fact, ART itself is associated with deleterious effects
on lipid profile and cardiovascular risk greater than those observed on mere exposure
to the virus. Therefore, the present study was based on the description of people living
with HIV̸AIDS in follow-up at the University Hospital Alcides Carneiro (HUAC), with
emphasis on the description of the lipid profile of this patients. The results were mostly
consistent with those presented in the literature, with most of the patients in the study
presenting total cholesterol (CT) and hypertriglyceridemia, in addition to low HDL. In
disagreement with what is broadly brought in in other studies however, an
unexpectedly small share had low LDL. Results were also concordant with the
literature regarding the comparison between the users of different antiretroviral
regimens, with patients who used protease inhibitors (PIs) with a higher frequency of
alterations in the lipid profile.