Perfil lipídico de mulheres portadoras da síndrome da apneia obstrutiva do sono.

Abstract

INTRODUCTION: OSAS is a chronic condition characterized by repeated episodes of upper airway obstruction during sleep, resulting in periods of apnea and being associated with several signs and symptoms of of sleep. It is known that the prevalence of apnea is higher in males and that the Estrogen acts as a protective factor. Dyslipidemia, on the other hand, is a condition clinical condition characterized by alterations in the concentrations of lipids and lipoproteins in the blood. So far, the literature does not contain large studies directly relating OSAS to changes in the lipid profile. Therefore, it is important to know whether the degree of apnea interferes with the lipid profile of patients. METHODS: The present study is clinical, observational, descriptive, with cross-sectional design and retrospective data collection. PSG of female patients with OSAS, abdominal USG and measurements of the following components were retrospectively reviewed: TG, TC, HDL and LDH RESULTS: 99 female patients with a mean age of 54.6 (±10 years) were included. ,2 years. SAH was present in 59 (61.5%), DM in 27 (27.8%), MS in 37 (37.4%) and NAFLD in 57 (57.6%). The average of the laboratory tests were: triglycerides= 182.2 ± 108.8 mg/dl (changed in 55 (56%)), total cholesterol = 205.4 ± 41.8 mg/dl (changed in 43 (43.9 %)), HDL= 53.7 ± 15 mg/dl (changed in 47 (47.5%)) and LDL= 118.8 ± 41.2 (changed in 38 (38.8%)). CONCLUSION: Although the majority of the sample had mild OSAS, there were significant laboratory alterations for dyslipidemia in more than half of the cases. In addition, OSAS was associated with other comorbidities such as SAH, DM and MS, finally we had a prevalence in more than half of the sample for NAFLD.