http://lattes.cnpq.br/1320985257919115; Silva, Wanessa Medeiros da.
Abstract:
Radiation can be defined as the irradiation of energy by any substance and can be divided
between electromagnetic and nuclear radiation. Exacerbated exposure to ultraviolet radiation can
harm our health and cause diseases such as skin cancer. An alternative to avoid this type of disease
is to adopt the recurrent use of sunscreens, especially chemical ones, as they contain natural
compounds in their composition. Flavonoids are a group of phenolics derived from the secondary
metabolism of plants of great importance among natural products that have a photoprotective
capacity. Quercetin is a flavonoid that can be isolated from apples, grapes, onions and leafy
plants. Rutin is a flavonoid that can be found and extracted from tomatoes, beans, red wine,
apples, black tea, onions, among others. The present study aimed to analyze the solar
photoprotection factor, in vitro, of the flavonoids quercetin and rutin. The solution of the natural
substance diluted in different concentrations of 50, 100, 500 and 1000 μg/mL was used and scans
were performed in a spectrophotometer at the wavelength of 290 to 320 nm with intervals of 5
nm every 5 minutes. The results were calculated according to the Mansur equation to determine
the sun protection factor. Both flavonoids studied showed a photoprotective capacity with SPF
greater than 6 at all concentrations, with those of 500 and 1000 μg/mL showing better results in
both experiments with SPF=25. Therefore, the flavonoids quercetin and rutin can be classified as
suitable for use in the production of natural sunscreens, by carrying out further experiments on
its toxicity.