AMADOR, Vinícius Costa.; RODRIGUES, Ravenna Lins.; OLIVEIRA, Felipe França de.; MAIA, Rafael Trindade.
Abstract:
Rice is an herbaceous plant in the grass family, from the genus Oryza,
which feeds more than half the human population and therefore has great global
importance. In spite of such importance, there are just a few studies to minimize the
problems intrinsic to the cultivation of these cereals. One of the main limiting factor in the
cultivation are rice weeds, due to competitor resources, inherent in a healthy
development, the chemical control is still the must importante form of weeds
management, where in many cases the cultivar suffers productive losses, by contact with
the herbicide. It is known that the superfamily of glutathione s-transferase (GSTs)
enzymes confer on rice (Oryza sativa), a biotic and abiotic aesthetic, acts on
biotransformation to protect against oxidative stress and excretion of xenobiotics,
including herbicide detoxification. It is necessary to explore the mechanism of interaction,
as well as the proteins with herbicides in question. Bioinformatics arises with the
molecular anchoring technique, which aims to suggest and explore possibles better
conditions of molecular interaction, to study and differentiate between a family of ligands
or inhibitors. Molecular docking is a broad-spectrum technique with high processing
speed and low cost. This work aims to elucidate an interaction of a GST family rice
protein and glyphosate herbicide, demonstrating its biotechnological importance and as
advantages for agroindustry and agrochemicals industry and for plant genetic
improvement, pointing to proteins related to tolerance to herbicides.