ARAÚJO, J. M.; http://lattes.cnpq.br/1810199012217691; ARAÚJO, Joany de Medeiros.
Résumé:
Aging is associated with cognitive decline and the consumption of essential fatty
acids (FAs) can modulate this function. Dietary lipids can make up brain tissue
and promote the fluidity of neuronal membranes, in addition to regulating
neurotrophins responsible for inducing neuronal survival, development and
function. Several scientific evidences have reported the positive effect of fatty
acids on rodent memory. However, the effects of caprine cream consumption
on the nervous system of aged rats they are not completely enlightened. Our
objective was to investigate the impact of goat cream supplementation on
memory parameters in elderly wistar rats. Two groups were formed: control
(CG) - treated with distilled water and goat cream (C) - treated with 2,000 mg of
goat cream / kg animal weight. For the concreteness of the study, the Open
Field Habituation Test and Object Recognition Test (ORT) were performed from
545 days of age. Results were statistically analyzed and the result was
considered significant when p <0.05. The Open Field Habituation test showed
that rats supplemented with goat cream reduced ambulation activity on the
second exposure to the apparatus, inferring memory consolidation (p <0.05).
The animals from the NC group also showed positive results regarding the
exploration rate in the object recognition test (ORT), where the animals
supplemented with goat cream explored the new object longer when compared
to the CG (p <0.05). Supplementation with goat cream seems to be efficient for
the memory of aged rats, but other results need to be explored in order to
identify the mechanisms that involve the action of GA with the improvement of
cognitive performance.
