CARDOSO, G. M. C. S.; http://lattes.cnpq.br/3211384711764419; CARDOSO, Gina Mara Coelho de Souza.
Resumen:
Clinical use of fluoride gels for topical application by professionals is indicated for
prevention and treatment of dental caries and dental erosion due to the ability to
interact with the process of demineralization - remineralization of tooth mineral
matrix. The general objective of this work was to evaluate the physicochemical
characteristics of topical gels for professional dental remineralization specified in the
records granted by ANVISA. There were fifteen (15) valid records, relating to sixteen
(16) products of fluoride gel use dental topic has been verified. As for these products,
there were eight (8) neutral fluoride gels and eight (8) acidulated fluoride gels. All
products contain in their composition sodium fluoride and the most used polymer for
gel formation is hydroxyethyl cellulose. All acidulated fluoride gels have in their
composition 1.23 % fluorine ions and all neutral fluoride gels contain 2 % NaF in its
composition, as stated in the registration process at ANVISA. In 60 % of valid
registration process there was information about the pH of the product. In the survey
conducted in March 2014 in dental stores at Federal District (DF), it was observed
the marketing of two products from the same manufacturer, being one neutral fluoride
gel and one gel of acidulated fluoride. For physicochemical characterization, nine
bottles of 200 ml of fluoride gel were acquired in DF: three of acidulated fluoride gel
within the validity, three of acidulated fluoride gel out of date and three of neutral
fluoride gel. These products were evaluated by the following techniques: Scanning
Electron Microscopy (SEM), Energy Dispersive X-ray Spectrometry (EDS), Fourier
Transform Infrared Spectrometer (FTIR), Differential Scanning Calorimetry (DSC),
Thermogravimetry (TG) and evaluation of the hydrogen potential (pH). The chemical
elements identified by EDS analysis, in regions without clusters and with clusters of
dehydrated samples, are consistent with the chemical composition of the products
declared by the manufacturer to ANVISA. The FTIR outcomes showed no significant
changes among analyzed samples. Different results among samples were observed
during DSC and TGA tests, this is probably related to dehydration of the samples and
the formation of agglomerates. More studies about the physicochemical
characteristics of topical gels for professional dental remineralization are needed to
support the development of specific technical standards.