Avaliação do fator de fotoproteção solar do óleo essencial da Lavandura hybrida grosso: Um estudo in silico e in vitro.

Abstract

The radiation emitted by the sun consists of a set of waves called the solar electromagnetic spectrum. This spectrum is divided into wavelength intervals (»), with the ultraviolet (UV), visible (VIS) and infrared (IR) bands being the most prominent. Ultraviolet rays provide many benefits to living beings, including the absorption of vitamin D, which is vital to the human body. However, excessive exposure to the sun can lead to serious health problems, including skin and mouth cancer. Among the methods for reducing the adverse effects of solar radiation, the application of broad-spectrum sunscreens is recommended. In this sense, discovering new methods of preventing sun damage is important, especially when it comes to products of natural origin, which are more accessible in economic terms. The aim of this study was therefore to evaluate the in silico and in vitro sun protection factor of Lavandula hybrida grosso essential oil. In vitro, a solution of the natural substance diluted in different concentrations was used and scanned using a spectrophotometer. In the in silico test, the main component linalool had its biological properties evaluated using the PASSONLINE software. The results were calculated according to the Mansur equation to determine the in vitro sun protection factor where the essential oil showed photoprotective capacity with an SPF greater than 6 at all concentrations, and the in silico linalool for antioxidant and radioprotective activities obtained a PA of 0.380 and 0.396 respectively. Therefore, in both studies, the essential oil in question can be considered a promising candidate for future in vivo research.