Uso da coenzima Q10 no tratamento da síndrome dos ovários policísticos: revisão interativa.

Abstract

Polycystic Ovary Syndrome (PCOS) is a disease that produces endocrine alterations, causing hormonal imbalance, generating metabolic alterations in women such as: infertility, hirsutism or menstrual dysregulation, more serious complications such as cardiovascular system and other comorbidities. Supplementation with Coenzyme Q10, a fat-soluble benzoquinone, antioxidant, has shown beneficial effects in the treatment of PCOS, as a complementary alternative to changes in lifestyle and diet, and associated or not with medication. Therefore, the present study aimed to elucidate scientific evidence on the use and effect of Coenzyme Q10 supplementation on the metabolic alterations observed in PCOS. The search was performed in the Google Scholar and Pub Med databases, with the keywords “Polycystic Ovary Syndrome” and “Coenzyme Q10”. Publications involving only human beings, published in the last 7 years, corresponding to 2017 to 2024, were included. The studies demonstrate that CoQ10 supplementation from 8 weeks of treatment, at a dose of 100mg to 200mg, is associated with a reduction in BMI, blood pressure, inflammatory markers, and a reduction in insulin resistance. Regarding infertility, through the regulation of the hormones FSH and LH, resulting in an improvement in the ovulation rate, an increase in the number of follicles, increasing the probability of pregnancy.