SILVA, E. A.; http://lattes.cnpq.br/4224099114720481; SILVA, Edenilton Alves da.
Resumo:
Dengue is a viral infection transmitted by the bite of female Aedes aegypti
mosquitoes. The virus has four known serotypes: DENV-1, DENV-2, DENV-3, and
DENV-4, all of which belong to the Flaviviridae family. The disease generally
manifests in two forms: Classic Dengue, characterized by high fever (up to 40°C),
joint pain, muscle pain, and retro-orbital pain; and Severe Dengue, which is mainly
characterized by the onset of hemorrhagic events. The global incidence of dengue
has increased drastically in recent decades, with Brazil being particularly affected,
accounting for 82% of the suspected cases and deaths worldwide. Thus, the present
study aimed to analyze the main hematological changes associated with dengue
virus infection. This is a narrative literature review, aiming to identify articles that
depict the current situation of hematological changes in patients with dengue; and it
was conducted in the scientific databases PubMed, Science Direct, Google Scholar,
and the Virtual Health Library (BVS). Eighteen articles were selected on the topic,
which provided information on the hematological profile of individuals with dengue
virus. It was found that the most frequently associated hematological changes in
individuals infected with the dengue virus were thrombocytopenia, leukopenia, and
increased hematocrit.