Perfil de consumo de dipirona, ibuprofeno e paracetamol em uma farmácia comunitária privada no município de Cuité - PB.

Abstract

The indiscriminate use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as dipyrone, ibuprofen and paracetamol has raised public health concerns due to potential risks associated with their inappropriate administration. These drugs are widely used for pain relief, fever control and inflammation reduction, but high and indiscriminate consumption can lead to significant adverse effects, including gastrointestinal, cardiovascular and renal complications. Dipyrone, although rare in gastrointestinal effects, is banned in several countries due to the risk of agranulocytosis. Paracetamol, known for its hepatotoxicity in high doses, is an important cause of acute liver failure. Ibuprofen is associated with gastrointestinal and cardiovascular complications. This study investigated the consumption profile of dipyrone, ibuprofen and paracetamol in a private community pharmacy in Cuité-PB, focusing on understanding patterns of use and self-medication practices. A descriptive, observational, and exploratory approach was used to collect quantitative and qualitative data on the demand and dispensing of these medications throughout 2023. The results showed high sales of the medications in question; the most prevalent consumption was dipyrone (n=3,225), followed by paracetamol (n=601) and ibuprofen (n=378), with the highest number of dispensings in the first half of the year. The most sought-after pharmaceutical forms were tablets and capsules, and similar medications had the greatest share in sales. The findings highlight the need for more rigorous monitoring and the promotion of rational use of medications. Finally, education and adequate guidance by health professionals are

essential to ensure the safety of NSAIDs and minimize the risks associated with self- medication practices and indiscriminate use.