Atividade antifúngica do extrato de própolis vermelha frente a leveduras do gênero Candida isoladas da cavidade bucal.

Abstract

Candidiasisis a common opportunisticinfectionoccurring in the oral cavity. There are several Candida species that are part of the man microbiota and can be found in the oropharynx, mouth, bronchial secretions, folds of skin and vagina. The biological activity of propolis is attributed to substances derived from plants harvested for their production. Although this product is from animal origin, some chemical compounds of propolis are derived from botanical source used by the bees, particularly those with biological action. Therefore, this study aimed to identify which is the action of propolis on microorganisms present in the oral cavity, from the analysis of scientific production; a profile of oral health of patients seen in the dental office of the Family Health Strategy in São Bento-PB and its relation to susceptibility to oral candidiasis; identify the species of Candida and evaluate the antifungal activity of propolis, against yeasts of the oral cavity. There was a systematic literature review, the integrative type, in response to the first objective; to the achievement of other goals, made an exploratory research with quantitative approach, whose sample consisted of 152 patients treated at the dental office of ESF in São Bento-PB, saliva was collected with the aid of a swab, identification of Candida species was by CromCandida Agar. The extract of propolis from bee Apismellifera, originated from Dalbergiaecastophylum. The antifigic action of the extract was analyzed in four concentrations to 100%, 75%, 50% and 25%. In processing the data, the statistical package for social sciences (Statistical Package for Social Sciences - SPSS) was used, version 17. For analysis using descriptive statistics, and as a measure of central tendency average; and applying the Chi-square (X?) test, observing the values of the standard deviation (SD) and confidence interval (CI) in order to obtain the correlation between variables. In compliance with Resolution 466/12, the research was approved by the Federal University of Campina Grande Research Ethics Committee (UFCG / CFP), CAAEÉE 37184414.5.0000.5575 protocol. According to the results, it was necessary to research that studies with systematic reviews and randomized clinical studies with humans, as they were considered the greatest strength of evidence are carried out, so that one can have, more precisely, the action of propolis on microorganisms of the oral cavity; was found that the habits and oral hygiene conditions were poor, the predominant sex was female, the positivity for Candida the most prevalent species were C. albicans was also observed that the lower the concentration of propolis are the best halos inhibition.