Uso do extrato da Psidium guajava L. como alternativa aos antibióticos tradicionais.

Abstract

Amid the rise of antibiotic-resistant bacteria, medicine is increasingly seeking alternatives such as therapies or products that replace these drugs in the treatment of bacterial infections. In view of this, this Final Course Work seeks to analyze, based on the literature, the potential of the antimicrobial effect of Psidium guajava extracts and their use for the production of new antibiotics. The methodology used in this Final Course Work was the integrative literature review, which took place in the first semester of 2024. The strategy used was PICO, Google Scholar, PubMed and Scielo were used as data portals, for the research of several descriptors and one keyword: “Resistant Bacteria” “Bacteria” “Guava” “Antibiotics” “Antimicrobial Agent” and “Antimicrobial Activity” separated by the operators OR and AND to ensure the relationship or alternation between them. Zotero was used to organize the scientific papers found after the research, and Rayyan QRCI was used for the initial and in-depth analysis of the selected articles. The methanolic extract proved to be the most effective in relation to the use of other P. guajava extracts. In addition, some tested extracts were as effective as conventional antibiotics and others showed a synergistic effect in combination with these drugs. Based on the articles analyzed, it was possible to observe the effectiveness of the antimicrobial effect of Psidium guajava extracts, but also other effects relevant to medicine. Furthermore, P. guajava extracts have the potential to be used in the production of antimicrobial drugs.