SANTOS, Taires Aparecida Marinho dos.
Abstract:
Rational use of a drug will have as much to do with the form of administration as with the way it is stored. It is known that high microbial loads can compromise the stability of drugs, impairing their therapeutic efficacy. The aim of the present study was to perform the microbiological analysis of dipyrone-containing medications stored at home, seeking to demonstrate that microbial contaminations may be directly involved in the inadequate handling of drugs kept in homes, making it possible to draw up strategies that may reduce the risks associated with therapy drug therapy. Microbiological analyzes were performed on 10 liquid dipyrone samples, within their validity periods, in which contamination by bacteria and / or fungi was confirmed in 8 samples, all contaminations being within the established limits. The absence of pathogenic microorganisms such as S. aureus, Pseudomonas aeruginosai and Salmonella sp was detected, and the presence of E. coli was detected in 5 of 10 samples analyzed. The results showed the presence of bacteria and / or fungi in the majority of the samples, besides the presence of E. coli in half of the analyzed drugs, demonstrating the importance of the pharmaceutical professional in the orientation regarding the storage and correct use of the medicine.
