SILVA, M. J. R.; http://lattes.cnpq.br/3995332514560467; SILVA, Mikael Johnathan Ribeiro da.
Abstract:
The most frequent cause of Chronic Kidney Disease (CKD) in the world is Diabetes Mellitus (DM), since it can trigger the occurrence of metabolic and hemodynamic disturbances that increase vascular permeability and systemic arterial pressure, altering the regulation of intracapillary pressure, resulting in proteinuria. In this way, CKD arises from the progressive and irreversible decrease of excretory renal function, as a consequence of renal tissue damage, reduction in glomerular filtration rate and loss of nephrons. If it is impossible for the renal system to perform its functions, it is necessary to resort to alternative renal therapies, with hemodialysis being the most frequent in the world. Due to the already proven efficacy of yellow passion fruit peel flour in reducing glycemia and DM control, this study aimed to evaluate the effect of its supplementation on the clinical status and biochemical parameters of diabetic patients in hemodialysis therapy in the municipality of Patos/PB. The aim of this study was to administer the supplementation of 20 g/day of the flour during the 60-day period. The participants (n=24) were mostly males, with a mean age of 54 years and with Incomplete Elementary School as the predominant level of schooling. However, it was not possible to verify the efficacy of supplementation in relation to the variables related to the clinical examination of the patients, while the means of glycemia and total cholesterol decreased to the point of approaching the reference values, but did not present statistical difference when comparing the before and after groups intervention. In summary, it is necessary that other studies be carried out in this area, considering the evaluation of the supplementation for a longer period, with the help of a dietary management that ensures the highest levels of adequacy.
