SILVA, Lucicarla Maria da.
Abstract:
The request for a laboratory examination is a common practice when the health professional feels the need to evaluate and monitor the patient's condition, since the laboratory tests help these professionals to clarify the diagnosis and show whether the result of the treatment is satisfactory or not, factors such as These justify the need for results consistent with the actual situation of the patient. Hypertension and diabetes mellitus are chronic non-transmissible diseases, considered as public health problems, since it affects a considerable part of the Brazilian population, treatment is done continuously with antihypertensives and antidiabetics. The aim of this integrative review was to evaluate the antihypertensive and antidiabetic interference in laboratory tests. The research was done through electronic databases and collection of the library of the UFCG / CES, prioritizing materials published in the period from 2007 to 2017, totaling 61 materials for this study. Antihypertensive and antidiabetic agents, as well as other classes of medicinal products, have the capacity to alter the results of exams routinely in the functional evaluation of the main organs, such as captopril, which causes a false increase in fructosamine, a transient increase Of creatinine and urea and increased crystals in the urine; Hydrochlorothiazide increases urea, glucose, calcium and uric acid and AST and ALT enzymes and decreases potassium and sodium; Metformin decreases iron and triglycerides and causes increased lactate and urinary ketones and HDL; Glibenclamide increases total bilirubin, AST and glucose and causes hypoglycemia. These interferences most often occur in in vivo mechanisms, and may be considered negligible when the professionals involved know the drug in use by the patient and the changes caused by it, this knowledge, helps in the interpretation of the result and consequently in the closing of the diagnosis.
