Sistema computacional para biossensor baseado na ressonância de plasma de superfície.

Abstract

A surface plasmons resonance based biosensor, able to operate both in angular interrogation mode (AIM) and wavelength interrogation mode (WIM), is presented in this work. The proposed system uses biochip development at University Federal of Campina Grande to compose the sensitive surface, being first device that use the first optical biochip built in Brazil. Proposed biosensor uses a x86 architecture minicomputer, which is called Acquisition, Control, Processing, and Display Units (ACPDU) for biomolecular interactions analysis. Optical, microfluidic, mechanics and electronics elements were arranged to compose biosensor structure. ACPDU operating system has been customized to enhance response time. Each structure offer resources for analyzing and processing sign by embedded softwares specific. The morphology analysis of SPR curve combined with user techniques chooser, for resonance parameters get, assign the proposed solution a great tool for teaching and research. The tests confirmed equipment feasibility for biomolecular interactions analysis in both operation modes.