Avaliação de qualidade físico-quimica e microbiológica de tinturas de tansagem (plantago major L.).

Abstract

Medicinal plants are used in several communities as a therapeutic resource for the cure of various diseases. In folk medicine, great plantin tincture is recommended for the treatment of throat inflammation, as analgesic and general anti-inflammatory. This study aimed to evaluate parameters of microbiological and physicochemical quality and efficacy and to investigate the phytochemical groups of the great plantain tincture produced by CENEP - Nova Palmeira - PB. For the microbiological analysis, the pour plate count test was used. For the tincture antimicrobial efficacy proof, the agar diffusion method was used. The physico-chemical evaluation were performed by pH, density, dry residue tests and the phytochemical groups were identified by specific chemical reactions. Four samples prepared with the dry and fresh vegetable raw material were compared. From a microbiological viewpoint, all samples were within the pharmacopoeial limits, however, there was growth of S. aureus in one of the samples. Antimicrobial activity was observed only in the samples produced with the dry plant drug (inhibition halos between 10.3 and 11.7 mm) against S. pyogenes and S. aureus. Mean values of pH (5.39), density (0.9350 mg / mL) and dry matter (2.74%) were obtained and positive reaction for the presence of phenolic compounds and tannins. The data show the therapeutic potential, but it reinforces the importance of the way of obtaining standardization, as well as the quality of products of plant origin evaluation, in order to guarantee the constancy of therapeutic action and use safety.