Avaliação da resposta imunológica humoral à vacinação em alunas de Enfermagem contra o Vírus da Rubéola em uma IES.

Abstract

rubella is a disease characterized by rash beginning insidious by rash beginning insidious on the face, scalp and neck region, and it is also followed by involvement of all parts of the body. The same is caused by involvement of all parts of the body. The same is caused by the Rubivírus. Objective: to evaluate the number of students vaccinated with the MMR vaccine and who presented under serological evidence, evidence of antibodies that ensure immunological protection to the natural infection of rubella virus. Method: for this study were collected blood samples from 26 female students, usingthe techniques of enzyme-linked immunosorbent assay (ELISA), wint the use of diagnostic kits PISHTAZTEB ZAMAN DIAGNOSTIC ® for rubella. Serum samples were analyzed for students from 2st to 7th period of the degree course in nursing thatmade use of one dose of the MMR vaccine. The samples were collected on the premises of the institution itself. The analysis was performed in microplate reader 12-1 x 8 (96 wells) based on espectrofometria TEMOPLATE brand, model TP-Reader. IgG values above 10 Ui /ml was considered positive and values less than 10 Ui / ml were considered negative. For the data analysis was used the IBM SPSS Software version 22 (Statistical Package for the Social Science). Results and discussion: it was found that in 100% of samples tested there wereseroconversion, getting 213 UI/mL average (standard deviation 45,98). You can see that the largest media of seroconversion by age group was represented by students aged 20 to 29 years (233 UI/mL). Then the group of student with the age group between 15 and 19 years of age has submitted the second highest average of seroconversion (203,43 UI/mL) and the student aged 30 to 39 years presented the lowest average of seroconversion (145,83 UI/mL). Final consideration: it was found that in 100% of sample there was satisfactory and excellent soroconversion titration of IgG antibodies. The MMR vaccine was shown to be quite immunogenic, showing seroconversion in all age grow. The study studyshowed the population student there was a lasting response and consequently the guarantee to prevent a new infection.