SOUSA, Francisca Jocilânia Dantas de.
Resumen:
Vaccines are part of Brazil's history in many contexts. They arose from the need of the
population affected by certain diseases, which for many years caused high mortality rates and
were inserted in an impetuous environment. At the current juncture, vaccination is recognized
as a preventive intervention that impacts on the reduction of morbidity and mortality resulting
from immunopreventable diseases. In the face of new discoveries and analyzes related to the
Human Papilloma Virus still in the ascendancy, which, although delineated for more than five
decades, appears to us as little reflected and discussed by the population, we organized this
foundation in order to clarify punctually the contexts most evaluated and that must be taken
into account by both the academic population and society as a whole. The association of the
HPV virus with cervical cancer began in 1949, when pathologist George Papanicolaou
introduced the examination that through the technique of smearing material collected from the
vaginal mucosa can identify the presence of abnormal cells of the medium. This was an
epidemiological, analytical study with a quantitative approach. It sought to evaluate the
occurrence of post-vaccination adverse events against HPV according to the parameters
established by the PNI and the variables included in the Post Vaccination Adverse Event
Notification / Investigation Card, version August 2014, as well as the severity of these effects.
It is noteworthy that for the accomplishment of this study, all the requirements contained in
Resolution 466/12 of the National Health Council were met, which provides for research
involving human subjects, including prior approval by the Research Ethics Committee of the
Federal University of Campina Grande . The collected data were tabulated and analyzed in the
software Statistical Package for Social Sciences (SPSS), version 24.0 and the descriptive
statistics of frequencies, besides the analysis of correlations between the parameters presented
in the form of tables. Pain at the site after vaccine application was the most prevalent adverse
reaction, followed by swelling at the site. Most of the interviewees did not present systemic
manifestations and other types of manifestations and when they presented, the most prevalent
were headache, drowsiness and muscular pain. Statistically significant correlations were
found indicating that muscular pain and headache were the most enduring events, as well as
the predominance of interviewees of the black race in reports of neurological manifestations
and the lower presence of these adolescents in reports of headache and muscular pain, as well
as a relationship between participants who reported drowsiness with the presence of diabetes
and heart disease in the family. Subsequent investigations need to be conducted to elucidate
the nature of these relationships found in this research.
