Influência do óleo de gergelim, consumido durante a gestação e lactação e sua repercussão sobre o perfil bioquímico e parâmetros físicos e lipídico hepático da prole de ratas.

Abstract

Sesame oil is a source of monounsaturated fatty acids and polyunsaturated which have potentially important effects in the modulation of development processes, related to growth, body composition, development of neural function, immune and allergic responses, as well as the reduction of chronic diseases related to nutrition. The objective of this research is to verify the effects of sesame oil consumption on profiles biochemical, physical, and hepatic fat offspring of treated rats during pregnancy and lactation. Primiparous females were used, of Wistar lineage, to obtain offspring. After the diagnosis of pregnancy they received, during pregnancy and lactation, diets lipid content from different sources. Two groups were formed, the control group (C) (n = 17) - treated with 7% soybean oil and Sesame Oil Group (SOG) - (n = 10) - treated with 7% lipids derived from sesame oil. At 60 days, the rats were anesthetized and were soon made the murinometricas measures, with measurement of waist circumference, vertex-coccyx length, body weight, abdominal fat and calculate the body mass index; biochemical: total cholesterol, triglycerides, high-density lipoprotein and glucose; the liver was removed to analyze the content of liver lipid. The rats treated with sesame oil during pregnancy and lactation had a significant reduction in hepatic lipid, compared to the control group, however there was no significant change in offspring. As to the physical parameters, decreased length and reduced weight and abdominal fat SOG offspring compared to C. The biochemical data, the offspring of SOG mothers showed a significant increase in HDL cholesterol compared to the control group. According to the results, it can be concluded that the sesame oil during pregnancy and lactation is considered a good source of essential fatty acids, which increased HDL and reduced abdominal fat offspring. Moreover, from additional studies, justifying its use in humans, can be an important lipid option, to be prescribed to pregnant women with fatty liver, since it was observed efficacy in reducing maternal liver fat.