Avaliação dos efeitos de uma dieta à base de castanha de caju durante a gestação e lactação sobre a murinometria e perfil bioquímico da prole.

Abstract

During pregnancy occur metabolic and nutritional changes in maternal body to ensure an environment conducive to fetal development. Intrauterine nutrition and the first years of life is extremely relevant, for the insults suffered during this critical period of development correlate directly with the onset of chronic diseases in adulthood. Some long-chain polyunsaturated fatty acids such as docosahexaenoic acid and arachidonic of omega 3 and 6 series have important structural effects on organ development, especially in the retina and brain. Almond Cashew Nut has in its composition oleic fatty acids, linoleic and linolenic acids. Through the above the present study aimed to verify the effects on a diet of cashew base during pregnancy and lactation on the murinométricos parameters and biochemical profile of the offspring. Primiparous females were used to obtain the litters. After confirmation of pregnancy through the vaginal smear, females were divided into three groups: control group (GS) - 7% soybean oil; Group cashew nut normolpídico (GCN) -7% lipids from cashew nuts and cashew Group chestnut hyperlipidic (HCG) -20% lipids from cashew nuts. Females received the experimental diets during pregnancy and lactation. After weaning mothers were euthanized and the offspring started to receive commercial diet up to 60 days, where murinométricas evaluations were conducted, collected blood samples and liver for later analysis. To determine blood glucose was used ACCU-Chek blood glucose meter. Quantification of total cholesterol, triglyceride and HDL-C was performed using enzymatic kits Labtest® with reading in a spectrophotometer. The end of the experiment and found that the fat diet imposed on mothers during pregnancy and lactation caused a delay in body weight and growth of offspring and altered lipid profile thereof, raising cholesterol and triglyceride levels but reduced the deposition of liver fat (P <0, 05). However it is noteworthy that the normolipídica diet cashew-based reduced the deposition of fat in the liver mothers and lowered cholesterol levels in the offspring (P <0.05). Depending on the amount of chestnut flour consumed both the physical parameters such as biochemical have changed.