SILVA, S. L.; http://lattes.cnpq.br/3725591148226412; SILVA, Shellygton Lima.
Résumé:
Dermatophytoses are skin infections caused by fungi, which are limited to keratinized portions of the skin, hair or nails. Knowing the limited therapeutic tools and increased fungal resistance, it is perceived in the natural products important alternatives to be investigated. The aim of this study was to determine the physical and chemical parameters of powders and infusions of Camellia sinensis (L.) Kuntze and their potential antifungal against dermatophytes. The analysis of the moisture content, total ash and acid insoluble ash, dry and antifungal susceptibility of infusion were carried out in different forms of the vegetable drug. The data of moisture content were 11.33% and 11.19%, for the drug, bulk and sachet respectively. The content of total ash and acid insoluble ash, also fulfilled the parameters of literature, except for the content of acid insoluble ash for bulk drug with value greater than 1.5%. The soluble solids content in liquid extractor (dry) demonstrated that infused when subjected to extraction processes with agitation provided higher yields. In the evaluation of the antifungal susceptibility by microdilution technique, there was no inhibition of growth of the strains Trichophyton rubrum, when exposed to infusions from C. sinensis. Therefore realized with the physical and chemical tests, except for the insoluble ash content in acid for bulk vegetable drug, both ways of obtaining (bulk and sachet) are within the limits specified in the literature and that the tested infusions were not able to inhibit the strains Trichophyton rubrum, but for future studies it is suggested to isolate and identify the compound (s) present (s) that responsible plant drug (lo) by a potential antifungal activity against this dermatophyte.
