FARIAS, Fernanda Aracelly Dias de.
Abstract:
Understanding the characteristics and pattern of adverse drug reactions is essential information for the safety of drug users, an activity intrinsic to the interests of Pharmacoepidemiology. Drugs can cause a variety of blood dyscrasias, by interfering with hematopoiesis in the bone marrow or by damaging mature blood cells by antibodies. drugs, hypersensitivity, immune defects secondary to viral infections, or mixed or unknown mechanisms. The most common drug-induced haematological disorders are thrombocytopenia, neutropenia, and agranulocytosis. Laboratory diagnosis is indispensable and the hemogram is the exam that quantitatively and qualitatively assesses the cellular elements of the blood. The present work aimed to perform a bibliographic research in order to identify the possible hematological alterations induced by drugs, being chosen some classes of these. During the review we found articles that comprehended the subject of the work comprehensively and clearly, published mainly between 2004 and 2014, covering the period of the last 10 years. Antipsychotic and anticonvulsant drugs were the ones that showed induction of more hematological alterations. Clinical follow-up and monitoring are of paramount importance to avoid drug problems.
