Casos registrados de citomegalovirose diagnosticadas no Hospital Universitário Alcides Carneiro (HUAC) da Universidade Federal de Campina Grande, Paraíba.

Abstract

Cytomegalovirus (CMV) is a DNA virus belonging to the family herpesviridae sharing functions such as latency and reactivation. Transmission may occur by body fluids and secretions in general can cause congenital infections. Clinical manifestations can be generated late as deafness during childhood hepatosplenomegaly in babies, among others. The laboratory diagnosis is essential for prevention and treatment. The most used technique is the ELISA test. The present study aimed to of the prevalence of CMV infections in the University Hospital Alcides Carneiro de Campina Grande - Paraíba. This is a survey of exploratory, descriptive and analytic research with quantitative approach noting age, sex, and serologic markers - IgG and IgM, from the results of the examinations from the ELISA test in the months of September to December of 2009 in the Laboratory of Molecular Biology of the HUAC. We found a positive IgG and IgM antibodies to CMV reagents average of 97 (45.53%). The most prevalent age group infected was between 20-39 years (61.8%), with women more soroprevalente with 79 cases (81.44%). There is a positive and definite relationship between seropositivity to CMV and young women in Campina Grande, Paraíba, and due to this fact, it is believed that congenital CMV infection in this region can be quite frequent. It is hoped that the study will contribute to that has a new and broader view of the risk of infection by cytomegalovirus and give subsidies to a more concrete action from public health agencies to the elucidation of prevention and therapeutic intervention in this process in the region.