ARAÚJO, Vivianne Souto de.
Abstract:
Currently, one of the classes of drugs most used by the Brazilian population are anti-inflammatory Nimesulide is a nonsteroidal anti-inflammatory drug with analgesic, antitérmicas and anti-inflammatory properties, with much less consumed due present incidence of side effects. For the production of these drugs are required by the agencies responsible for manufacturing some minimum criteria that followed them ensure adequate quality, however the information disclosed on this production still leave doubts as to the veracity of this patient quality, thus the control quality consists of a set of operations that allow you to check if the product is in conformity with the specifications laid down by the Pharmacopoeia. The present work aimed to select the most marketed anti-inflammatory in the municipality of Cuité-PB, and evaluate the physical and chemical quality of these tablets from different pharmaceutical companies. Analysis of average weight, hardness, friability, disintegration and uniformity of dosage unit assay was performed. The tests were performed according to the Brazilian Pharmacopoeia 5th Edition, 2010. These results indicated that the samples of the generic 1 were outside the conformity of the hardness tester, obtaining an average hardness of 28.45 N and samples of 1 Generic Similar and were outside of limits for friability test. In the rest of the reviews all samples were approved, meeting the quality parameters required by the Brazilian Pharmacopoeia 5th edition, with properties that qualify them as suitable for consumption.
