SANTOS, J. A. M.; http://lattes.cnpq.br/0342787503858361; SANTOS, John Anderson Macêdo.
Resumo:
This paper describes the synthesis of various (alkyl and aryl) amidoximes using different functionalized nitriles in aqueous medium at room temperature. The new methodology has proven to be effective in a wide variety of aromatic nitriles containing donor groups and electron withdrawing providing the corresponding amidoximes with yields ranging from moderate to excellent without further purification. Tests involving alkyl nitriles to obtain the alkyl amidoximes were not satisfactory, being observed only the formation of alkyl amide. Additionally, the method proved to be regional and quimiosseletivo because there was no addition or isomerization of the double bond of E-cinamonitrila, and the reaction led exclusively to E-cinamoamidoxima obtained in 72% yield after 21 hours of reaction.
