COUTINHO, Carmem Lúcia Cavalcanti.
Resumo:
The sling technique by transobturator approach is effective for the treatment of
women with Stress Urinary Incontinence and has a high cure rate and improved
quality of life with low complication rates. This work aimed to develop and produce,
polycaprolactone, screen for use in Sling surgery and to perform comparative
analyses of this material with a polypropylene bladder, used commercially. The
survey was developed in the laboratory of evaluation and development of
Biomaterials in the Northeast-CERTBIO. Two samples were used to screen; a made
in the laboratory and another used commercially. Been evaluated physical and
chemical compositions of the Polycaprolactone (PCL) and Polypropylene (PP)
screens, through the following techniques: infrared Spectroscopy in the region with a
Fourier transform (FTIR), x-ray Diffraction (XRD) and scanning electron microscopy
(SEM), surface tension, traction mechanical essays and Cytotoxicity test. You can
check by the FTIR analysis, that the trainer material of fabrics was just poliproplieno
and polycaprolactone, for examining the computer spectrogram. The XRD analysis
corroborated with the results obtained in the FTIR analysis, which indicated that the
material was PP screens and PCL, showing a characteristic you might like to look of
these polymers. Also, through the analysis of DRX, it was possible to o bserve the
degree of crystallinity indicating the PP has higher degree of crystallinity the PCL.
One can prove that the PP has higher mechanical strength than the PCL, checking
so that the PP is more brittle than the PCL. The analysis of surface tension showed
that both screens have partial wettability due to cavity present on the surface of the
canvas. The biocompatibility of the compounds has been confirmed with the
Cytotoxicity test and it showed low cytotoxicity in two screens.